HSPMdb Accession NoHSPMDB002352
PMID26566002
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound NameAV287
IUPAC NameN-[2-(1H-1,3-benzodiazol-2-yl)ethyl]-4-(dimethylsulfamoyl)benzamide
SMILESCN(C)S(=O)(=O)C1=CC=C(C=C1)C(=O)NCCC1=NC2=C(N1)C=CC=C4
ClassCOMAS Library
IC50 (µM)51.2
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (FITC-casein)
DiseaseBacterial infection

Structure



HSPMDB002352

AV287

Physicochemical Properties