HSPMdb Accession No | HSPMDB002349 |
PMID | 26566002 |
Target | Hsp100 |
HSP Name | ClpXP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of protease activity |
Compound Name | AV286 |
IUPAC Name | N-(2-(Thien-2-yl)oxazol-4-yl)methyl 4-(benzylaminocarbonylamino)benzamide |
SMILES | O=C(NCc1ccccc1)Nc2ccc(cc2)C(=O)NCc3coc(n3)c4sccc4 |
Class | COMAS Library |
IC50 (µM) | 2.1 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Substrate degradation assay (GFP-ssrA) |
Disease | Bacterial infection |