HSPMdb Accession NoHSPMDB002349
PMID26566002
TargetHsp100
HSP NameClpXP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound NameAV286
IUPAC NameN-(2-(Thien-2-yl)oxazol-4-yl)methyl 4-(benzylaminocarbonylamino)benzamide
SMILESO=C(NCc1ccccc1)Nc2ccc(cc2)C(=O)NCc3coc(n3)c4sccc4
ClassCOMAS Library
IC50 (µM)2.1
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (GFP-ssrA)
DiseaseBacterial infection

Structure



HSPMDB002349

AV286

Physicochemical Properties