| HSPMdb Accession No | HSPMDB002348 |
| PMID | 26566002 |
| Target | Hsp100 |
| HSP Name | ClpXP |
| Organism | Bacteria |
| Localization | Cytosol |
| Enzymatic activity | Inhibition of protease activity |
| Compound Name | AV321 |
| IUPAC Name | N-(2-(Thien-2-yl)oxazol-4-yl)methyl 4-(2-(3-(But-3-ynyl)-3H-diazirin-3- yl)ethyloxycarbonylamino)benzamide |
| SMILES | O=C(Nc1ccc(cc1)C(=O)NCc2coc(n2)c3sccc3)OCCC4(CCC#C)N=N4 |
| Class | COMAS Library |
| % Enzymatic Inhibition/Fold Change | 85% at 100 uM |
| Site of Interaction | Nucleotide binding domain |
| Type of Enzymatic Assay | Substrate degradation assay (GFP-ssrA) |
| Disease | Bacterial infection |
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