| HSPMdb Accession No | HSPMDB002346 |
| PMID | 26566002 |
| Target | Hsp100 |
| HSP Name | ClpXP |
| Organism | Bacteria |
| Localization | Cytosol |
| Enzymatic activity | Inhibition of protease activity |
| Compound Name | AV280 |
| IUPAC Name | N-(2-(Thien-2-yl)oxazol-4-yl)methyl 1-(3,4-dimethylbenzyl)-1H-pyrazolo[3,4-b]pyridine5-carboxamide (AV280) |
| SMILES | Cc1ccc(Cn2ncc3cc(cnc23)C(=O)NCc4coc(n4)c5sccc5)cc1C |
| Class | COMAS Library |
| % Enzymatic Inhibition/Fold Change | 90% at 100 uM |
| Site of Interaction | Nucleotide binding domain |
| Type of Enzymatic Assay | Substrate degradation assay (GFP-ssrA) |
| Disease | Bacterial infection |
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