| HSPMdb Accession No | HSPMDB002345 |
| PMID | 26566002 |
| Target | Hsp100 |
| HSP Name | ClpXP |
| Organism | Bacteria |
| Localization | Cytosol |
| Enzymatic activity | Inhibition of protease activity |
| Compound Name | AV145 |
| IUPAC Name | N-(2-(Thien-2-yl)oxazol-4-yl)methyl 1-Isopropyl-1H-pyrazolo[3,4-b]pyridine-5- carboxamide |
| SMILES | CC(C)n1ncc2cc(cnc12)C(=O)NCc3coc(n3)c4sccc4 |
| Class | COMAS Library |
| % Enzymatic Inhibition/Fold Change | 98% at 100 uM |
| Site of Interaction | Nucleotide binding domain |
| Type of Enzymatic Assay | Substrate degradation assay (GFP-ssrA) |
| Disease | Bacterial infection |
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