HSPMdb Accession NoHSPMDB002343
PMID26566002
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameAV245
IUPAC Name4-methanesulfonamido-N-{[2-(thiophen-2-yl)-1,3-oxazol-4-yl]methyl}benzamide
SMILESC[S](=O)(=O)Nc1ccc(cc1)C(=O)NCc2coc(n2)c3sccc3
ClassCOMAS Library
IC50 (µM)8
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002343

AV245

Physicochemical Properties