HSPMdb Accession No | HSPMDB002342 |
PMID | 26566002 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | AV224 |
IUPAC Name | 4-(dimethylsulfamoyl)-N-{[2-(thiophen-2-yl)-1,3-oxazol-4-yl]methyl}benzamide |
SMILES | CN(C)[S](=O)(=O)c1ccc(cc1)C(=O)NCc2coc(n2)c3sccc3 |
Class | COMAS Library |
IC50 (µM) | 6 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |