HSPMdb Accession NoHSPMDB002341
PMID26566002
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameAV243
IUPAC Name4-(cyclopropylsulfamoyl)-N-{[2-(thiophen-2-yl)-1,3-oxazol-4-yl]methyl}benzamide
SMILESO=C(NCc1coc(n1)c2sccc2)c3ccc(cc3)[S](=O)(=O)NC4CC4
ClassCOMAS Library
IC50 (µM)5.9
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002341

AV243

Physicochemical Properties