HSPMdb Accession No | HSPMDB002338 |
PMID | 26566002 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | AV241 |
IUPAC Name | N-(2-(Thien-2-yl)oxazol-4-yl)methyl 4-(tert-butyloxycarbonylamino)benzamide |
SMILES | CC(C)(C)OC(=O)Nc1ccc(cc1)C(=O)NCc2coc(n2)c3sccc3 |
Class | COMAS Library |
IC50 (µM) | 1.8 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |