HSPMdb Accession NoHSPMDB002335
PMID26566002
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameAV279
IUPAC NameN-(2-(Thien-2-yl)oxazol-4-yl)methyl 1-(4-Isopropylbenzyl)-1H-pyrazolo[3,4-b]pyridine5-carboxamide
SMILESCC(C)c1ccc(Cn2ncc3cc(cnc23)C(=O)NCc4coc(n4)c5sccc5)cc1
ClassCOMAS Library
IC50 (µM)5.1
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002335

AV279

Physicochemical Properties