HSPMdb Accession No | HSPMDB002335 |
PMID | 26566002 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | AV279 |
IUPAC Name | N-(2-(Thien-2-yl)oxazol-4-yl)methyl 1-(4-Isopropylbenzyl)-1H-pyrazolo[3,4-b]pyridine5-carboxamide |
SMILES | CC(C)c1ccc(Cn2ncc3cc(cnc23)C(=O)NCc4coc(n4)c5sccc5)cc1 |
Class | COMAS Library |
IC50 (µM) | 5.1 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |