HSPMdb Accession No | HSPMDB002334 |
PMID | 26566002 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | AV265 |
IUPAC Name | N-(2-(Thien-2-yl)oxazol-4-yl)methyl 1-(4-Cyanobenzyl)-1H-pyrazolo[3,4-b]pyridine-5- carboxamide |
SMILES | O=C(NCc1coc(n1)c2sccc2)c3cnc4n(Cc5ccc(cc5)C#N)ncc4c3 |
Class | COMAS Library |
IC50 (µM) | 5 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |