HSPMdb Accession NoHSPMDB002332
PMID26566002
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameAV264
IUPAC NameN-(2-(Thien-2-yl)oxazol-4-yl)methyl 1-(3-Cyanobenzyl)-1H-pyrazolo[3,4-b]pyridine-5- carboxamide
SMILESO=C(NCc1coc(n1)c2sccc2)c3cnc4n(Cc5cccc(c5)C#N)ncc4c3
ClassCOMAS Library
IC50 (µM)4
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002332

AV264

Physicochemical Properties