HSPMdb Accession NoHSPMDB002324
PMID26566002
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameAV145
IUPAC NameN-(2-(Thien-2-yl)oxazol-4-yl)methyl 1-Isopropyl-1H-pyrazolo[3,4-b]pyridine-5- carboxamide
SMILESCC(C)n1ncc2cc(cnc12)C(=O)NCc3coc(n3)c4sccc4
ClassCOMAS Library
IC50 (µM)10
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002324

AV145

Physicochemical Properties