HSPMdb Accession NoHSPMDB002313
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameML38
IUPAC NameMethyl (E)-4-((2-methyl-3-(3,4,5-trimethoxyphenyl)acryloyl)oxy)benzoate
SMILESCOC(=O)c1ccc(OC(=O)C(/C)=C/c2cc(OC)c(OC)c(OC)c2)cc1
ClassNon beta lactone inhibitor (AV170 derivative)
% Enzymatic Inhibition/Fold Change10% at 1 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002313

ML38

Physicochemical Properties