HSPMdb Accession No | HSPMDB002310 |
PMID | 26083639 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | ML73 |
IUPAC Name | Methyl 4-((2-(3,4,5-trimethoxybenzyl)acryloyl)oxy)benzoate |
SMILES | COC(=O)c1ccc(OC(=O)C(=C)Cc2cc(OC)c(OC)c(OC)c2)cc1 |
Class | Non beta lactone inhibitor (AV170 derivative) |
% Enzymatic Inhibition/Fold Change | 60% at 1 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |