HSPMdb Accession No | HSPMDB002308 |
PMID | 26083639 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | ML95 |
IUPAC Name | Methyl (R)-4-((2-(3,4,5-trimethoxybenzyl)butanoyl)oxy)benzoate |
SMILES | CC[C@H](Cc1cc(OC)c(OC)c(OC)c1)C(=O)Oc2ccc(cc2)C(=O)OC |
Class | Non beta lactone inhibitor (AV170 derivative) |
% Enzymatic Inhibition/Fold Change | 10% at 10 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |