HSPMdb Accession No | HSPMDB002302 |
PMID | 26083639 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | ML43 |
IUPAC Name | Methyl 4-((2-methyl-3-(3,4,5-trimethoxyphenyl)propanoyl)oxy)benzoate |
SMILES | COC(=O)c1ccc(OC(=O)C(C)Cc2cc(OC)c(OC)c(OC)c2)cc1 |
Class | Non beta lactone inhibitor (AV170 derivative) |
% Enzymatic Inhibition/Fold Change | 95% at 10 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |