HSPMdb Accession NoHSPMDB002300
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameML73
IUPAC NameMethyl 4-((2-(3,4,5-trimethoxybenzyl)acryloyl)oxy)benzoate
SMILESCOC(=O)c1ccc(OC(=O)C(=C)Cc2cc(OC)c(OC)c(OC)c2)cc1
ClassNon beta lactone inhibitor (AV170 derivative)
% Enzymatic Inhibition/Fold Change90% at 10 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002300

ML73

Physicochemical Properties