HSPMdb Accession NoHSPMDB002298
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameML95
IUPAC NameMethyl (R)-4-((2-(3,4,5-trimethoxybenzyl)butanoyl)oxy)benzoate
SMILESCC[C@H](Cc1cc(OC)c(OC)c(OC)c1)C(=O)Oc2ccc(cc2)C(=O)OC
ClassNon beta lactone inhibitor (AV170 derivative)
% Enzymatic Inhibition/Fold Change55% at 100 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002298

ML95

Physicochemical Properties