HSPMdb Accession NoHSPMDB002295
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameML15
IUPAC NameMethyl 3,5-dimethyl-4-((3-(3,4,5-trimethoxyphenyl)propanoyl)oxy)benzoate
SMILESCOC(=O)c1cc(C)c(OC(=O)CCc2cc(OC)c(OC)c(OC)c2)c(C)c1
ClassNon beta lactone inhibitor (AV170 derivative)
% Enzymatic Inhibition/Fold Change0-5% at 100 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002295

ML15

Physicochemical Properties