HSPMdb Accession NoHSPMDB002294
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameML37
IUPAC NameMethyl 3-methyl-4-((3-(3,4,5-trimethoxyphenyl)propanoyl)oxy)benzoate
SMILESCOC(=O)c1ccc(OC(=O)CCc2cc(OC)c(OC)c(OC)c2)c(C)c1
ClassNon beta lactone inhibitor (AV170 derivative)
% Enzymatic Inhibition/Fold Change20% at 100 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002294

ML37

Physicochemical Properties