HSPMdb Accession NoHSPMDB002268
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameML23
IUPAC Namemethyl 3-{[3-(3,4,5-trimethoxyphenyl)propanoyl]oxy}benzoate
SMILESCOC(=O)c1cccc(OC(=O)CCc2cc(OC)c(OC)c(OC)c2)c1
ClassNon beta lactone inhibitor (AV170 derivative)
% Enzymatic Inhibition/Fold Change55% at 1 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002268

ML23

Physicochemical Properties