HSPMdb Accession NoHSPMDB002267
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameML03
IUPAC NameIsopropyl 4-((3-(3,4,5-trimethoxyphenyl)propanoyl)oxy)benzoate
SMILESCOc1cc(CCC(=O)Oc2ccc(cc2)C(=O)OC(C)C)cc(OC)c1OC
ClassNon beta lactone inhibitor (AV170 derivative)
% Enzymatic Inhibition/Fold Change60% at 1 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002267

ML03

Physicochemical Properties