HSPMdb Accession NoHSPMDB002266
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameML33
IUPAC NameMethyl 4-((3-(1H-indol-3-yl)propanoyl)oxy)benzoate
SMILESCOC(=O)c1ccc(OC(=O)CCc2c[nH]c3ccccc23)cc1
ClassNon beta lactone inhibitor (AV170 derivative)
% Enzymatic Inhibition/Fold Change70% at 1 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002266

ML33

Physicochemical Properties