HSPMdb Accession No | HSPMDB002259 |
PMID | 26083639 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | ML24 |
IUPAC Name | 2-acetylphenyl 3-(3,4,5-trimethoxyphenyl)propanoate |
SMILES | COc1cc(CCC(=O)Oc2ccccc2C(C)=O)cc(OC)c1OC |
Class | Non beta lactone inhibitor (AV170 derivative) |
% Enzymatic Inhibition/Fold Change | 8% at 10 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |