HSPMdb Accession NoHSPMDB002258
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameML31
IUPAC NameMethyl 4-(hept-6-ynoyloxy)benzoate
SMILESCOC(=O)c1ccc(OC(=O)CCCCC#C)cc1
ClassNon beta lactone inhibitor (AV170 derivative)
% Enzymatic Inhibition/Fold Change0-5% at 10 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002258

ML31

Physicochemical Properties