HSPMdb Accession NoHSPMDB002256
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameML68
IUPAC Namemethyl 4-{[3-(thiophen-2-yl)propanoyl]oxy}benzoate
SMILESCOC(=O)c1ccc(OC(=O)CCc2sccc2)cc1
ClassNon beta lactone inhibitor (AV170 derivative)
% Enzymatic Inhibition/Fold Change0-5% at 10 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002256

ML68

Physicochemical Properties