HSPMdb Accession NoHSPMDB002252
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameML57
IUPAC NameMethyl 4-((3-(3-acetylphenyl)propanoyl)oxy)benzoate
SMILESCOC(=O)c1ccc(OC(=O)CCc2cccc(c2)C(C)=O)cc1
ClassNon beta lactone inhibitor (AV170 derivative)
% Enzymatic Inhibition/Fold Change0-5% at 10 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002252

ML57

Physicochemical Properties