HSPMdb Accession NoHSPMDB002250
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameML28
IUPAC Name4-(Dimethylamino)phenyl 3-(3,4,5-trimethoxyphenyl)propanoate
SMILESCOc1cc(CCC(=O)Oc2ccc(cc2)N(C)C)cc(OC)c1OC
ClassNon beta lactone inhibitor (AV170 derivative)
% Enzymatic Inhibition/Fold Change10% at 10 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002250

ML28

Physicochemical Properties