HSPMdb Accession NoHSPMDB002248
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameML05
IUPAC Name4-Methoxyphenyl 3-(3,4,5-trimethoxyphenyl)propanoate
SMILESCOc1ccc(OC(=O)CCc2cc(OC)c(OC)c(OC)c2)cc1
ClassNon beta lactone inhibitor (AV170 derivative)
% Enzymatic Inhibition/Fold Change30% at 10 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002248

ML05

Physicochemical Properties