HSPMdb Accession NoHSPMDB002243
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameMLIH18
IUPAC Name4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl 3-(3,4,5-trimethoxyphenyl)propanoate
SMILESCOc1cc(CCC(=O)Oc2ccc(cc2)c3noc(C)n3)cc(OC)c1OC
ClassNon beta lactone inhibitor (AV170 derivative)
% Enzymatic Inhibition/Fold Change95% at 10 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002243

MLIH18

Physicochemical Properties