HSPMdb Accession NoHSPMDB002235
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameML74
IUPAC Name4-(Methoxycarbonyl)phenyl 3,4,5-trimethoxybenzoate
SMILESCOC(=O)c1ccc(OC(=O)c2cc(OC)c(OC)c(OC)c2)cc1
ClassNon beta lactone inhibitor (AV170 derivative)
% Enzymatic Inhibition/Fold Change75% at 100 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002235

ML74

Physicochemical Properties