| HSPMdb Accession No | HSPMDB002231 |
| PMID | 26083639 |
| Target | Hsp100 |
| HSP Name | ClpP |
| Organism | Bacteria |
| Localization | Cytosol |
| Enzymatic activity | Inhibition of peptidase activity |
| Compound Name | AV134 |
| IUPAC Name | 1-(2,2-dimethylpropanoyl)-N-[4-(2-oxopyrrolidin-1-yl)phenyl]piperidine-4-sulfonamide |
| SMILES | CC(C)(C)C(=O)N1CCC(CC1)S(=O)(=O)NC1=CC=C(C=C1)N1CCCC1=O |
| Class | Non beta lactone inhibitor (AV170 derivative) |
| % Enzymatic Inhibition/Fold Change | 0-5% at 100 uM |
| Site of Interaction | Nucleotide binding domain |
| Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
| Disease | Bacterial infection |
Loading Please Wait ...