HSPMdb Accession No | HSPMDB002230 |
PMID | 26083639 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | ML68 |
IUPAC Name | methyl 4-{[3-(thiophen-2-yl)propanoyl]oxy}benzoate |
SMILES | COC(=O)C1=CC=C(OC(=O)CCC2=CC=CS2)C=C1 |
Class | Non beta lactone inhibitor (AV170 derivative) |
% Enzymatic Inhibition/Fold Change | 5% at 100 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |