HSPMdb Accession NoHSPMDB002228
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameML18
IUPAC Name4-((3-(3,4,5-trimethoxyphenyl)propanoyl)oxy)benzoic acid
SMILESCOc1cc(CCC(=O)OC2CCCCC2)cc(OC)c1OC
ClassNon beta lactone inhibitor (AV170 derivative)
% Enzymatic Inhibition/Fold Change20% at 100 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002228

ML18

Physicochemical Properties