HSPMdb Accession No | HSPMDB002227 |
PMID | 26083639 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | ML09 |
IUPAC Name | Cyclohexyl 3-(3,4,5-trimethoxyphenyl)propanoate |
SMILES | COC(=O)c1ccc(OC(=O)CCc2cccc(c2)C(C)=O)cc1 |
Class | Non beta lactone inhibitor (AV170 derivative) |
% Enzymatic Inhibition/Fold Change | 10% at 100 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |