HSPMdb Accession NoHSPMDB002227
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameML09
IUPAC NameCyclohexyl 3-(3,4,5-trimethoxyphenyl)propanoate
SMILESCOC(=O)c1ccc(OC(=O)CCc2cccc(c2)C(C)=O)cc1
ClassNon beta lactone inhibitor (AV170 derivative)
% Enzymatic Inhibition/Fold Change10% at 100 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002227

ML09

Physicochemical Properties