HSPMdb Accession NoHSPMDB002225
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameML92
IUPAC NameMethyl 4-((3-(3,4-dimethoxyphenyl)propanoyl)oxy)benzoate
SMILESCOc1cc(CCC(=O)Oc2ccc(cc2)N(C)C)cc(OC)c1OC
ClassNon beta lactone inhibitor (AV170 derivative)
% Enzymatic Inhibition/Fold Change85% at 100 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002225

ML92

Physicochemical Properties