HSPMdb Accession NoHSPMDB002220
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameMLIH19
IUPAC Name4-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl 3-(3,4,5-trimethoxyphenyl)propanoate
SMILESCOc1cc(CCC(=O)Oc2ccc(cc2)C(C)=O)cc(OC)c1OC
ClassNon beta lactone inhibitor (AV170 derivative)
% Enzymatic Inhibition/Fold Change0-5% at 100 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002220

MLIH19

Physicochemical Properties