HSPMdb Accession NoHSPMDB002219
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameML27
IUPAC Name4-acetylphenyl 3-(3,4,5-trimethoxyphenyl)propanoate
SMILESCCCCOC(=O)CCc1cc(OC)c(OC)c(OC)c1
ClassNon beta lactone inhibitor (AV170 derivative)
% Enzymatic Inhibition/Fold Change0-5% at 100 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002219

ML27

Physicochemical Properties