HSPMdb Accession No | HSPMDB002218 |
PMID | 26083639 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | ML14 |
IUPAC Name | Butyl 3-(3,4,5-trimethoxyphenyl)propanoate |
SMILES | COc1cc(CCC(=O)Oc2ccc(cc2)c3noc(C)n3)cc(OC)c1OC |
Class | Non beta lactone inhibitor (AV170 derivative) |
% Enzymatic Inhibition/Fold Change | 0-5% at 100 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |