HSPMdb Accession NoHSPMDB002217
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameMLIH18
IUPAC Name4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl 3-(3,4,5-trimethoxyphenyl)propanoate
SMILESCOC(=O)c1cccc(OC(=O)CCc2cc(OC)c(OC)c(OC)c2)c1
ClassNon beta lactone inhibitor (AV170 derivative)
% Enzymatic Inhibition/Fold Change95% at 100 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002217

MLIH18

Physicochemical Properties