HSPMdb Accession NoHSPMDB002215
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameML03
IUPAC NameIsopropyl 4-((3-(3,4,5-trimethoxyphenyl)propanoyl)oxy)benzoate
SMILESCOC(=O)c1ccc(OC(=O)CCc2c[nH]c3ccccc23)cc1
ClassNon beta lactone inhibitor (AV170 derivative)
% Enzymatic Inhibition/Fold Change0-5% at 100 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002215

ML03

Physicochemical Properties