HSPMdb Accession NoHSPMDB002212
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameML16
IUPAC NameMethyl 4-((3-(3,5-dimethoxy-4-(prop-2-yn-1-yloxy)phenyl)propanoyl)oxy)benzoate
SMILESC(Nc1nc(NCc2ccccc2)c3ccccc3n1)c4ccccc4
ClassNon beta lactone inhibitor (AV170 derivative)
% Enzymatic Inhibition/Fold Change100% at 100 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002212

ML16

Physicochemical Properties