| HSPMdb Accession No | HSPMDB002211 |
| PMID | 26083639 |
| Target | Hsp100 |
| HSP Name | ClpP |
| Organism | Bacteria |
| Localization | Cytosol |
| Enzymatic activity | Inhibition of protease activity |
| Compound Name | E2 |
| IUPAC Name | 3-(4-methoxyphenyl)-4-(pent-4-yn-1-yl)oxetan-2-one |
| SMILES | COC1=CC=C(C=C1)C1C(CCCC#C)OC1=O |
| Class | Non beta lactone inhibitor |
| % Enzymatic Inhibition/Fold Change | 15% at 1 uM |
| Site of Interaction | Nucleotide binding domain |
| Type of Enzymatic Assay | Substrate degradation assay (GFP-ssrA) |
| Disease | Bacterial infection |
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