HSPMdb Accession NoHSPMDB002209
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound NameAV170
IUPAC Name4-acetylphenyl 3-(3,4,5-trimethoxyphenyl)propanoate
SMILESCOC1=CC(CCC(=O)OC2=CC=C(C=C2)C(C)=O)=CC(OC)=C1OC
ClassNon beta lactone inhibitor
% Enzymatic Inhibition/Fold Change10% at 1 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (GFP-ssrA)
DiseaseBacterial infection

Structure



HSPMDB002209

AV170

Physicochemical Properties