HSPMdb Accession NoHSPMDB002202
PMID26083639
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound NameD3
IUPAC Name3-(non-8-en-1-yl)-4-(pent-4-yn-1-yl)oxetan-2-one
SMILESC=CCCCCCCCC1C(CCCC#C)OC1=O
ClassNon beta lactone inhibitor
% Enzymatic Inhibition/Fold Change90% at 10 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (GFP-ssrA)
DiseaseBacterial infection

Structure



HSPMDB002202

D3

Physicochemical Properties