| HSPMdb Accession No | HSPMDB002190 |
| PMID | 26083639 |
| Target | Hsp100 |
| HSP Name | ClpP |
| Organism | Bacteria |
| Localization | Cytosol |
| Enzymatic activity | Inhibition of protease activity |
| Compound Name | AV166 |
| IUPAC Name | (2Z)-3-(3,4-dimethoxyphenyl)-1-{3-[(2-oxo-2-phenylethyl)sulfanyl]-4H-1,2,4-triazol-4-yl}prop-2-en-1-one |
| SMILES | COC1=C(OC)C=C(\C=C/C(=O)N2C=NN=C2SCC(=O)C2=CC=CC=C2)C=C1 |
| Class | Non beta lactone inhibitor |
| % Enzymatic Inhibition/Fold Change | 75% at 100 uM |
| Site of Interaction | Nucleotide binding domain |
| Type of Enzymatic Assay | Substrate degradation assay (GFP-ssrA) |
| Disease | Bacterial infection |
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