HSPMdb Accession NoHSPMDB002170
PMID26083639
TargetHsp100
HSP NameClpP
OrganismHuman
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameD3
IUPAC Name3-(non-8-en-1-yl)-4-(pent-4-yn-1-yl)oxetan-2-one
SMILESC=CCCCCCCCC1C(CCCC#C)OC1=O
ClassNon beta lactone inhibitor
% Enzymatic Inhibition/Fold Change40% at 100 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)

Structure



HSPMDB002170

D3

Physicochemical Properties