HSPMdb Accession NoHSPMDB002167
PMID26083639
TargetHsp100
HSP NameClpP
OrganismHuman
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameAV167
IUPAC Name4-(1,3,4-oxadiazol-2-yl)phenyl 2-{naphtho[2,1-b]furan-1-yl}acetate
SMILESO=C(CC1=COC2=C1C1=C(C=CC=C1)C=C2)OC1=CC=C(C=C1)C1=NN=CO1
ClassNon beta lactone inhibitor
% Enzymatic Inhibition/Fold Change100% at 100 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)

Structure



HSPMDB002167

AV167

Physicochemical Properties