HSPMdb Accession No | HSPMDB002161 |
PMID | 26083639 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | AV170 |
IUPAC Name | 4-acetylphenyl 3-(3,4,5-trimethoxyphenyl)propanoate |
SMILES | COC1=CC(CCC(=O)OC2=CC=C(C=C2)C(C)=O)=CC(OC)=C1OC |
Class | Non beta lactone inhibitor |
% Enzymatic Inhibition/Fold Change | 80% at 1 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |